Birgid Schlindwein's

Hypermedia Glossary Of Genetic Terms

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Karyotype A photomicrograph of an individual's chromosomes arranged in a standard format showing the number, size, and shape of each chromosome type; used in low-resolution physical mapping to correlate gross chromosomal abnormalities with the characteristics of specific diseases.
Related Terms:
Chromosome The term was proposed by Waldeyer (1888) for the individual threads within a cell nucleus (gk. chroma, colour; soma, body). The self-replicating genetic structures of cells containing the cellular DNA that bears in its nucleotide sequence the linear array of genes. In prokaryotes, chromosomal DNA is circular, and the entire genome is carried on one chromosome. Eukaryotic genomes consist of a number of chromosomes whose DNA is associated with different kinds of proteins.
Physical map A map of the locations of identifiable landmarks on DNA (e.g., restriction enzyme cutting sites, genes), regardless of inheritance. Landmarks include restriction endonuclease recognition sites, DNA sequence and chromosomal bands. Distance is measured in base pairs. For the human genome, the lowest-resolution physical map is the banding patterns on the 24 different chromosomes; the highest-resolution map would be the complete nucleotide sequence of the chromosomes.

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Programming: Herbert Maier
Database: Birgid Schlindwein. Please contact me if you encounter any mistakes or if you are missing anything
© Dr. Birgid B. Schlindwein
last update of the database 10/01/2006